Research Goal

The American College of Radiology Imaging Network (ACRIN) is conceived as an integrated group of imaging researchers, other physician specialists, and basic and clinical scientists, patient advocates and a wide array of research support personnel.  In the next funding period ACRIN will continue to pursue its broad goal of: 

Through clinical trials of diagnostic imaging and image-guided therapeutics technologies, ACRIN seeks to develop information that:

  • improves the length and quality of cancer patients' lives
  • results in the earlier diagnosis of cancer

Primary Research Objectives

ACRIN has developed three primary research objectives that will drive scientific strategy and clinical trial development over the next funding period. These objectives support ACRIN’s broad goal by establishing imaging as an important tool in the development and monitoring of targeted interventions for cancer treatment and prevention.

  1. Screening of populations at high risk for cancer, including:
  • tailored, organ-specific screening;
  • combining in vitro and imaging techniques; and
  • surveillance for recurrence.
  1. Diagnosing and staging disease to guide targeted therapy, including:
  •  anatomical and functional characterization;
  •  image-guided therapy; and
  •   imaging phenotype.
  1. Investigations of biomarkers of treatment response, including:
  • general response markers (anatomic and functional); and 
  • targeted response markers (perfusion), and adaptive trials.

Secondary Objectives

ACRIN’s secondary objectives are critical for the continued advancement of medical imaging research and serve both ACRIN and the broader cancer research community:

1.      Develop an imaging core laboratory and related services;

2.      Establish a culture for imaging research;

3.      Support the development of imaging informatics standards; and

4.      Collaborate with the cancer research community.