This section describes the research goals and strategies underlying ACRIN clinical trials, the steps involved in the protocol development process, the responsibilities of the protocol team, and the site approval process. It allows you to review specific trial objectives related to patient diagnosis and treatment and to the radiology and cancer research community. Step-by-step instructions, along with templates for completing required forms, are available to help to demystify the process of applying to become an ACRIN clinical trial site. You will also find links to the identified strategies for each disease site committee as well as to handbooks and manuals on conducting ACRIN trials.