Whole-Body MRI in the Evaluation of Pediatric Malignancies

Protocol Documents

Protocol-ACRIN 6660 Amendment 5, 11.22.06 [PDF]

SOC-ACRIN 6660 Amendment 5, 11.22.06 [PDF]

Principal Investigator: Marilyn J. Siegel, MD

Status:  Analysis & Publications in Process

Main Objective: To compare the diagnostic performance of whole-body fast MRI with that of conventional imaging (the combination of chest CT, scintigraphy (bone or MIBG) and abdominal/pelvic CT/MRI as indicated) for detecting distant metastases for use in staging non-CNS small cell solid tumors in the pediatric population. There is an optional PET component of this study.

Participants: Male or female participants age 21 or younger, with newly diagnosed solid small cell tumors, not of the central nervous system, including but not limited to rhabdomyosarcoma, Ewing's sarcoma family of tumors (ESFT), and neuroblastoma.