Multicenter Feasibility Study of Percutaneous Radiofrequency Ablation of Hepatocellular Carcinoma in Cirrhotic Patients

Protocol Documents

Protocol-ACRIN 6673 Amendment 3, 2.26.08 [PDF]

SOC-ACRIN 6673 Amendment 3, 2.26.08 [PDF]

Informed Consent-ACRIN 6673 [DOC]


Principal Investigator: Gerald Dodd, III, MD

Status: Accrual Complete

Main Objective: To estimate the proportion of participants undergoing solitary or repetitive percutaneous radiofrequency ablation treatment sessions whose livers have no identifiable tumor by CT scan at 18 months following initiation of therapy.

Participants: Adult patients with cirrhosis and hepatocellular carcinoma in whom surgical resection is contraindicated will be potential candidates for this study. Eligible participants will have no previous or current treatment(s) for hepatocellular carcinoma by any method (no radiation therapy, chemotherapy, chemoembolization, and cryo-ablation).